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Jan 21, 2020

Flow cytometry is an invaluable technique for the characterisation of highly heterogeneous cell populations.

Thanks to improvements in throughput, automation and multichannel detection capabilities, recent years have seen its use expand across a wide range of drug discovery applications.

In this article, we look at...

Jan 7, 2020

Despite major investment in the field, few cell therapies have gained regulatory approval with limited commercial success.

The success of therapeutic products is defined by three factors: safety, efficacy and scalability. Achieving these for cell therapy presents new challenges; overcoming transplant rejection (and...

Dec 10, 2019

Drug discovery teams combine specialists with in-depth knowledge from a variety of scientific disciplines. Such diversity in thought worlds poses a challenging exercise in cross-disciplinary collaboration and project coordination.

Based on a longitudinal field study of five projects in a leading pharmaceutical company,...

Nov 26, 2019

In this episode, we look at how commercial products and services are facilitating the automation of cell-based assays to advance drug discovery and accelerate the delivery of new medicines to patients.

Cell-based assays are vital tools in modern drug discovery. Live cell cultures that replicate in vivo physiological...

Nov 12, 2019

New immunotherapies that integrate innate and adaptive immune responses may increase efficacy against many cancers, and have the potential to expand the range of tumours and patients that can be treated with immunotherapy.

Over the past decade, insights into the molecular mechanisms that cancer cells use to evade...