Dec 22, 2017
This episode discusses how, in the complex drug discovery process, one of the looming questions for any new compound is how it will be metabolised in a human body. While there are several methods for evaluating this, one of the most common involves CYP2D6, the enzyme encoded by the cytochrome P450-2D6 gene. This enzyme is involved in metabolising a quarter of all commonly used medications, making it an important target for ADME and pharmacogenomics studies.
The original article this episode is based on was written by Dr Jenny Ekholm. If you'd like to view the original article then follow the link below:
You can also download the original article pdf here:
http://www.ddw-online.com/media/32/125925/(3)-long-read-sequencing.pdf