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Dec 11, 2018

Magnetic Resonance Imaging (MRI) can be used to provide quantitative measurements in the form of imaging biomarkers. These measurements have a number of attractive characteristics: They are non-invasive, can provide organ and lesion localisation of morphology, physiology and metabolism and can be repeated over time.

These characteristics enable monitoring of the biological impact of drugs and can be helpful in patient selection. With appropriate deployment they can assist in go/no-go decision making and in some cases can provide endpoints for late stage trials.

This episode describes the deployment and potential benefit of MRI biomarkers via a number of examples of their use in drug development in different disease areas.

Original article by Dr Geoff J.M. Parker

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