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Aug 11, 2020

Mitigation of COVID-19 pandemic requires a combination of effective epidemiological policies and the discovery/development of powerful drugs against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes this disease.

This 2 part episode series examines the major initiatives being explored at the...


Jul 28, 2020

The recent outbreak of COVID-19 has highlighted the need for fast and efficient development and production of vaccines for a whole gamut of pathogens, old and new.

Microfluidics technologies can be used to accelerate the vaccine development process in a number of ways, not least in the directed evolution of the strains...


Jul 14, 2020

In response to the COVID-19 pandemic, international scientists from academia and industry have pooled their expertise and resources to identify candidate compounds that inhibit the activity of the SARS-CoV-2 main protease, in order to develop a clinically effective antiviral.

The aptly named COVID-19 Moonshot aims to...


Jun 23, 2020

Live-cell imaging has transformed the study of cell behaviour and function. The technique allows researchers to monitor internal cell structures, interactions and processes in real-time, and over time.

In drug discovery, understanding the dynamic processes of cells provides an enhanced picture of drug pharmacology,...


Jun 9, 2020

New disease targets frequently emerge in literature, but the thorough target validation required to consider these targets for a drug discovery programme is often lacking.

In pharmacological or genetic perturbation studies using complex biological assays, undesired off-target effects cannot be easily distinguished from...