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Aug 21, 2018

Smac mimetics are a new class of targeted drugs being developed for the treatment of solid tumours and hematologic cancers. Smac mimetics specifically induce apoptotic cancer cell death and block pro-survival signalling in cancer cells.

This episode provides an overview of the biology of Smac, an endogenous pro-apoptotic molecule, and the development of Smac mimetics as a novel therapeutic approach to treat cancer.

This article was written by Dr Mark A. McKinlay

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