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Aug 13, 2019

The safety and efficacy of therapeutic drugs still requires improvement. However, the advent of both systems biology and precision medicine has stimulated a rethink on the process of therapeutic drug design and polypharmacology.

More recently, the definition of polypharmacology has morphed to represent therapeutic drugs that have been designed deliberately for multi-targeting that affords beneficial effects to the patient.

This emerging effort has been labelled ‘Systems Pharmacology’ and the products are referred to as multi-target or systems pharmacology drugs.

This episode is part 1 of 2 episodes on the topic of systems pharmacology, and covers ­­human complexity, systems biology and precision medicine.

Original article by Dr Kirkwood A. Pritchard Jr, Dr Dustin P. Martin and Dr Stephen Naylor

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