Oct 26, 2018
A successful high-throughput approach to reaction screening requires rational and systematic exploration of a broad set of variables to achieve optimization expeditiously.
There are many types of potential variables that can be screened. Even with the aid of high-throughput screening tools, chances are that it’s still unlikely to screen all the possible combinations of reaction variables a process chemist desires. A well-planned high-throughput approach enables scientists to more clearly see the “big picture”, quickly abandon disadvantaged routes and rapidly pinpoint advantageous and impactful conditions to focus on.
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