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Dec 22, 2017

This episode discusses how, in the complex drug discovery process, one of the looming questions for any new compound is how it will be metabolised in a human body. While there are several methods for evaluating this, one of the most common involves CYP2D6, the enzyme encoded by the cytochrome P450-2D6 gene. This enzyme...


Dec 20, 2017

This episode discusses how, in order to maintain a flow of innovative medicines there is a growing realisation that companies cannot allow the status quo to remain as it is and the need to identify sources of appropriate knowledge and expertise outside of their own organisations is paramount. This episode discusses...


Dec 11, 2017

This episode of the Drug Discovery World podcast is part two of two episodes that give an Overview of Companion Diagnostics in the Pharmaceutical Industry, with a specific focus on business models in this episode. It is based on an article in our Spring 2010 issue, written by By Dr Stephen Naylor who is Founder,...


Dec 6, 2017

This episode of the Drug Discovery World Podcast gives an Overview of Companion Diagnostics in the Pharmaceutical Industry. It is based on an article in our Spring 2010 issue, written by By Dr Stephen Naylor who is Founder, President and Chairman of MaiHealth Inc, and Toby Cole, who is Founder of Triad Group. We discuss...


Nov 29, 2017

This episode of the Drug Discovery World podcast addresses the issue of advancing the drug discovery pipeline with early stage In vitro ADME and toxicity testing. This episode discusses: the front line for in vitro ADME and toxicity innovation; current common hepatocyte formats; improvements to hepatocyte cultures;...